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K-means clustering analysis of amplicon sequence variants by animal demonstrated that NNMTi-treated DIO mice switched to LD had a distinct microbiome pattern that was highlighted by decreased Erysipelatoclostridium and increased Lactobacillus relative abundances compared to vehicle counterparts

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Metabolic research focus: Examined in obese rodent studies for changes in weight gain patterns, fat oxidation, and markers associated with lipolysis and lipogenesis